Roses have a special pigment molecule, a particular form of anthocyanin, responsible for all the rich red-to-blue shades in the petals that delight gardeners and attract pollinating insects. This molecule is different from the pigments in every other flowering plant; it is glycosylated at two positions instead of one.2 A single enzyme does the job at both points. Without the glycosylation reaction at both ends, the molecule is unstable and cannot be soluble in water in the vacuoles of the cells in which it operates. A team of Japanese scientists investigated how this double-glycosylation reaction system might have evolved. They could find no intermediate. Reporting in Nature,1 they said that while other flowers use derivatives from a singly-glycosylated form, “this is evolutionarily precluded in roses by their different glycosylation pattern, which may be unique to members of the Rosaceae” (emphasis added in all quotes). They also stated with puzzlement,It is a mystery why this particular glycosyltransferase evolved independently in roses. The novelty of the RhGT1 enzyme therefore lies not only in its ability to catalyse glycosylation at two different sites on the anthocyanidin molecule but also in its apparent absence from other species.They prepared a phylogenetic tree based on this type of pigment-preparing enzyme family, but it ended up with the rose family on a branch all by itself.1Ogata et al., “Plant biochemistry: Anthocyanin biosynthesis in roses,” Nature, 435, 757-758 (9 June 2005) | doi: 10.1038/nature435757a.2Glycosylation replaces an OH (hydroxyl) group with a glucoside. This is performed by an enzyme called a glycosyltransferase, in the case of roses, RhGT1.Here is a small gap, but a gap nonetheless; no evidence for the evolution of this complex molecule and the enzyme that knows how to operate it – just an unconfirmed prediction from evolutionary theory. Surprised? Question: was evolutionary theory of any value in this investigation?(Visited 6 times, 1 visits today)FacebookTwitterPinterestSave分享0
The Raptors got 32 points from Leonard as they dropped their second straight.The Rockets held a 7-point lead to start the fourth and pushed it to 10 before the Raptors scored five straight points, capped by a 3 from Norman Powell to get within 99-94 with about nine minutes left.Houston then used a 9-0 run to extend the lead to 108-94 about three minutes later. Rivers made a 3 late in that span before Tucker capped it by grabbing a steal and finishing with a layup.Toronto got within 10 after scoring four quick points later in the fourth, but a layup by Harden made it 117-105 with about 90 seconds left.Houston led by as many as 22 early, but Toronto used a 41-point second quarter to cut the lead to 70-61 at halftime. The Raptors opened the third quarter with a 9-4 run to get within 4, but Houston followed with a 18-4 spurt, with nine points each from Harden, to push it to 92-74 with about four minutes left in the quarter.ADVERTISEMENT SEA Games hosting troubles anger Duterte MOST READ Petra Kvitova-Naomi Osaka: Australian Open final from different perspectives NEW YORK, NEW YORK – JANUARY 23: James Harden #13 of the Houston Rockets celebrates after teammate Gerald Green dunked in the third quarter against the New York Knicks at Madison Square Garden on January 23, 2019 in New York City. Elsa/Getty Images/AFPHOUSTON — James Harden scored 35 points for his 22nd straight game with 30 or more and the Houston Rockets never trailed and held off a late charge for a 121-119 win over the Toronto Raptors on Friday night.After averaging 52.2 points over the last five games, capped by a franchise-record 61 in Wednesday’s win over the Knicks, Harden’s torrid scoring pace slowed a bit as all of Houston’s starters scored 10 points or more.ADVERTISEMENT ‘We are too hospitable,’ says Sotto amid SEA Games woes LATEST STORIES Grace Poe files bill to protect govt teachers from malicious accusations Oil plant explodes in Pampanga town Oil plant explodes in Pampanga town Don’t miss out on the latest news and information. PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss The Raptors got back on track after that, scoring the next 10 points, with two 3-pointers from Danny Green, to cut the lead to 92-84 with about a minute left in the third.TIP-INSRaptors: Jonas Valanciunas missed his 21st game with a dislocated left thumb. … Green and Pascal Siakam added 22 points each. … Serge Ibaka had 12 points and 14 rebounds.Rockets: Brandon Knight missed his seventh straight game with a sore left knee, but is expected to return Sunday. … Houston made its first 20 free throws on Friday night before a miss by Faried with 7:55 left in the fourth quarter. The Rockets finished 29 of 33 from the line.UP NEXTRaptors: Visit Dallas on Sunday night.Rockets: Host Orlando on Sunday night.Sports Related Videospowered by AdSparcRead Next Lacson backs proposal to elect president and vice president in tandem Eric Gordon led that group with 24, Kenneth Faried had 21, P.J. Tucker added 18 and Austin Rivers scored 13. Faried also had a season-high 14 rebounds and blocked two shots in his third game since signing with the Rockets to fill in with Clint Capela recovering from thumb surgery.Houston led by 11 points after two free throws by Harden with 1:14 remaining before the Raptors made three straight 3-pointers to cut the lead to 121-119 with 27.3 remaining. Gordon missed a 3 to give the Raptors a chance, but Kawhi Leonard’s 3-point attempt was short.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine football chiefSPORTSWin or don’t eat: the Philippines’ poverty-driven, world-beating pool starsIt’s the 22nd straight game where Harden has led his team and Houston’s opponent in scoring, which moves him past Michael Jordan for the second-longest streak in NBA history behind Wilt Chamberlain, who did it in 40 in a row.Harden’s stretch of 30-point games is the fourth-longest in league history, behind three streaks by Chamberlain of 25, 31 and 65 games. Harden was 15 of 15 on free throws, but struggled from long-range, shooting just 2 of 13 on 3-point attempts. The strong play of Faried gave Harden some much-needed help Friday and The Beard will get another reinforcement Sunday night when Chris Paul is expected to return after missing 17 games with a strained left hamstring. US judge bars Trump’s health insurance rule for immigrants Private companies step in to help SEA Games hosting View comments
2007 Vawdon Cup winners, the Canterbury Bulldogs, claimed the scalp of Penrith in the opening round of the Men’s Premier League with a 8 – 6 victory. Easts put eleven past Manly with Matt Garthon being the recipient on four occasions. Touchdowns to Jamie Stowe and Dean Wilbow was not enough for Parramatta with the Sharkies winning by one. Dylan Hennessey got off to a stellar start to the season with a hat-trick enabling his Hornsby Lions to half the points on offer against Wests.In the Women’s Premier League, Wests got their campaign off to a winning start over Wollongong. Manly got up by one over Cronulla while Easts defeated the 2007 State Cup Champs, Canterbury, 3 – 1. Wests had a win over Penrith in the newly created Mixed Premier League division. Menai and Parramatta could not be separated with a 8 touchdowns apiece. The Coasties threw the gauntlet down to the rest of the competition with a 10 – 1 victory over the Easts Roosters. The Berryman boys proved valuable additions to the Dolphins line-up with three touchdowns between them.Men’s Premier League ResultsCronulla Sharks – 3 (Mitchell Brown 2, Rhys Bevan) defeated Parramatta Eels – 2 (Jamie Stowe, Dean Wilbow)Wests Magpies – 6 (Robert Nakhla 2, Edwin Farrah, Michael Moussa, Cameron Nicholls, Adrian Tan) drew with Hornsby Lions – 6 (Dylan Hennessey 3, Michael Abood, Heath Cooper, Jonathan Palau)Easts Roosters – 11 (Matt Garthon 4, Michael Stone 3, Christian Frost, Jonathan Rooke, Hayden Ruawai, Elijah Van Der Kwast) defeated Manly Sea Eagles – 5 (Jono Bailey, Joe Biskup, Sion Cousins, Mark Leonard, Andrew Windsor)Canterbury Bulldogs – 8 (Joel Willoughby 3, Matt Prowse 2, Stuart Brierty, Mark Heiss, Stephen Roberts) defeated Penrith Panthers – 6 (Dean McKechine 2, Nathan Byrnes, Grant Harris, Shane Lee, Ben Moylan)Women’s Premier League ResultsWests Magpies – 7 (Bonjani Mali 2, Nicky Albery, Amanda Dodson, Stacey Lapham, Tara Mohi, Tini Mohi) defeated Wollongong Devils – 3 (Kylie Evans, Stephanie Jackson, Cara Zaremski)Manly Sea Eagles – 3 (Te Aroha Paki, Rebecca Laing, Phillipa Robinson) defeated Cronulla Sharks – 2 (Brandi Elliot, Justine Johnston)Easts Roosters – 3 (Alison Bradley, Peta O’Connor, Maribel Ziade) defeated Canterbury Bulldogs – 1 (Jennifer Winchester)Mixed Premier League ResultsParramatta Eels – 8 (Ricky Hetherington, Mark Kovacic, Liam Simbolon, 5 scoreres not listed) drew with Menai Bulls – 8 (Matthew Fairbirne, Mark Lancaster, Michelle Lane, Christopher Suter. 4 scoreres not listed)Wests Magpies – 8 (Teava Terangi 3, Kate Hilyard, 4 scorers not listed) defeated Penrith Panthers – 3 (Rebecca Jones, Kyle Joyce, 1 scorer not listed)Central Coast Dolphins – 10 (Peter Sanders 4, Putatau Berryman 2, Nash Beeby, Harry Berryman, Kimberly Irwin, Kate Podryhula) defeated Easts Roosters – 1 (Mika Tagelagi)The remaining divisions (Men’s Division 1, Women’s Division 1, Mixed Division 1, Men’s Division 2, Women’s Division 2, Men’s Senior, and Men’s Masters) commence this Friday, 18 July 2008.For more details, visit the NSWTA Vawdon Cup website – http://www.sportingpulse.com/assoc_page.cgi?c=1-714-0-45019-0
Chelsea boss Sarri to go back to Empoli for Hamed Junior Traoreby Carlos Volcano10 months agoSend to a friendShare the loveChelsea boss Maurizio Sarri is ready to go back to Empoli for a new signing.Local media sources say Empoli youngster Hamed Junior Traore is interesting Sarri, who is tapping his old network for information on the midfielder.The 18 year-old is shining for Empoli coach Beppe Iachini and come to the attention of Sarri.The former Empoli coach is set to call president Fabrizio Corsi about a price for Traore.The Ivorian was outstanding for Empoli in defeat to Sampdoria last weekend. TagsTransfersAbout the authorCarlos VolcanoShare the loveHave your say
zoom Marshall Islands-incorporated containership charter owner Global Ship Lease (GSL) is gearing up to launch its proposed notes offering aimed at collecting between USD 350 and USD 400 million.The company said it has mandated advisors to arrange a series of investor meetings relating to the non-registered 5-year notes offering.GSL intends to use the proceeds from the offering, together with borrowings under a new super senior secured term loan facility, to refinance its existing first priority secured notes due 2019 and repay all outstanding borrowings and terminate its revolving credit facility and secured term loan.In a separate announcement the charter owner said that it has received updated broker valuations of its 18 vessels that reflect aggregate appraised values as at September 19, 2017 of USD 262.5 million (excluding charters) and USD 481.0 million (including charters).“The valuations give effect to the company’s previously announced extension of two of its charters with CMA CGM and take into account the re-delivery of the OOCL Tianjin, which is expected to take place on October 28, 2017, following notice received from the charterer,” GSL explained.Furthermore, GSL added that it was looking into re-deployment alternatives for the vessel.Global Ship Lease owns 18 vessels with a total capacity of 82,312 TEU and an average age of 12.7 years.As disclosed, all 18 vessels are currently fixed on time charters, 15 of which are with French liner major CMA CGM. The average remaining term of the charters at August 31, 2017 is 3.0 years or 3.3 years on a TEU weighted basis.
APTN National NewsMetis and non-status Indians won a “huge” victory Tuesday when the Federal Court of Canada ruled they fall under the federal government’s responsibility.It took years to get to this point, but the Congress of Aboriginal Peoples called the ruling a victory that was worth the wait.“We’re pleased. It’s a start. It’s a huge decision. It really has brought forward that Metis and non-status Indians are now recognized,” said a spokesperson for CAP who added more information will be available at a news conference Tuesday afternoon in Ottawa. “We will be responding in-depth once our legal has given more in-depth view of the potential impacts.”The ruling means Metis peoples are the responsibility of the federal government and can negotiate treaties and issues such as education, health and tax exemptions.However, the court didn’t order the government to begin negotiations. So when, and if, that happens remains in question.“The evidence concerning non-status Indians establishes that such persons were considered within the broad class of ‘Indians,’” said Justice Michael Phelan “The situation regarding Metis was more complex.”Phelan said nevertheless, Metis generally are often treated as Indians and have similar limitations, as well as suffer the same burdens and discrimination.More to come …
APTN National News OTTAWA–Public Safety Minister Vic Toews has taken on a “John Wayne attitude towards First Nation people” through his government’s plan to create a 50 RCMP officer task force and introduce tougher penalties to fight the underground tobacco trade, according to the Mohawk Council of Akwesasne.Toews announced Tuesday that in addition to a new anti-contraband tobacco unit, the government would introduce a bill to set mandatory minimum jail terms for people involved in the black market tobacco trade.“Sending additional troops from the RCMP isn’t going to resolve the contraband issue,” said a statement from Akwesasne Grand Chief Mike Mitchell. “There are already an insurmountable number of external policing agencies surrounding Akwesasne with the same goal.”Toews’ office did not respond to a request for comment.The RCMP said in an email to APTN National News that the new task force would get no new money and the cost would be absorbed under the existing budget. The RCMP also acknowledged that the rate of tobacco smuggling is decreasing.“The RCMP contraband tobacco seizures have declined over the past few years, which indicates that our efforts have an impact,” said an emailed statement from the RCMP. “However, it remains robust and a lucrative activity for organized crime.”The RCMP said the new task force would deployed “in areas known to have the highest level of contraband tobacco activity” including southern Ontario and the “central St. Lawrence seaway,” which is in and around Akwesasne Mohawk territory.The majority of black market tobacco flows from the U.S., through Akwesasne and into markets across Canada. There are also informal cigarette factories in Kahnawake, which sits next to Montreal, and Six Nations, which is also home to an established tobacco firm called Grand River Enterprises.Akwesasne has also seen a high level of marijuana, cocaine and human trafficking flow through its territory and the presence of organized crime elements has created tensions with local residents.The Akwesasne council, however, said no amount of policing could ever stem the flow of smuggling because it thrives from the jurisdictional tangle that covers the Mohawk territory. Akwesasne district Chief Steve Thomas said Toews should have first visited and met with the people of Akwesasne before launching another wrong-headed plan against the tobacco trade.“(Toews) would see that the problem isn’t the people of Akwesasne, but the multitude of borders that dissect Akwesasne into two countries, two provinces and one state,” said Thomas, in the statement. “The international boundary line zigzags around islands in the St. Lawrence River, making it extremely difficult for contraband to be seized and this weakness has been exploited by external criminal organizations.”The territory of Akwesasne, which sits about 120 kilometres west of Montreal, crosses the Quebec, Ontario and New York State borders.“The long-term solution…is removing the international boundary to one side or the other of Akwesasne…This would make our community whole again and the jurisdictional issues we face would cease to exist,” said Mitchell.Akwesasne is currently negotiating with the Ontario and Quebec governments to legalize the tobacco trade through internal self regulation.In the statement, the Akwesasne council said it is trying to replace the tobacco economy, which has kept the community from falling into abject poverty, with other types of economic development. The Mohawks own “nearly a hundred miles of islands” in the St. Lawrence River and are looking to develop cottage and tourism industries.“Harsher sentences and more police are not the solution to a larger economic issue,” said the statement from the Akwesasne Mohawk Council. “Minister Toews seems to be bent on becoming a poster child of Idle No More with his John Wayne attitude towards First Nations people.”First Nations people introduced Europeans to tobacco and the plant is used in sacred ceremonies. Many Mohawks see the tobacco trade as a right and do not recognize international boundaries imposed by nations they view as foreign.
The Toronto Blue Jays are inching closer to acquiring 2012 Cy Young award winner R.A. Dickey from the New York Mets, according to multiple sources.There were several other teams that were strongly interested in the services of Dickey, but the Mets decided to channel their negotiations with the Blue Jays and cut off all other discussions with the other teams, according to CBSSports.com.As of Saturday morning a major league executive aware of the negotiations told ESPNNewYork.com that both teams are working towards completing the trade.The Mets have discussed acquiring the Blue Jays top catching prospect Travis d’Arnaud, who they previously did not want to include, and center fielder Anthony Gose.Last season while playing in Triple-A in Las Vegas, the 23-year-old d’Arnaud had a batting average of .333, on base percentage of .380, a slugging average of .595 and 16 home runs.Dickey has yet to discuss extension talks, nor has he been asked to take a physical according to sources close with ESPNNewYork.com.The 38-year-old Dickey put together impressive numbers to win the 2012 Cy Young award. He led the NL with 233 2/3 innings pitched and finished second with an ERA of 2.73. He also led the league in strikeouts with 230 and owns a lifetime career ERA of 3.98 over 10 major-league seasons.Dickey, who is under contract with the Mets next season for $5 million, attempted to negotiate an extension with the club, but both sides were approximately $6 million apart. The Mets offered Dickey a two-year extension worth $20 million, while Dickey requested a two-year extension for $26 million.The knuckleballer made his frustrations known publically about the negotiations while attending a holiday party earlier this week at Citi Field for children affected by Hurricane Sandy.“In the context of the market, you want what you think is fair,” Dickey told reporters. “I feel like we’re asking for less than what’s fair because that’s how it’s been for me.”
Ohio State coaches Mark Mitchell (left) and Kevin McGuff (right) watch OSU’s 82-63 loss to Michigan State in the Big Ten tournament. Credit: Kevin Stankiewicz | Asst. Sports EditorNot too long ago, the Ohio State women’s basketball team was a unit with all the answers.OSU had won 11 straight games, the outright Big Ten regular-season title was within its grip and at least a No. 2 seed in the NCAA tournament was nearly a lock, with a top seed a realistic proposal.Now, just a couple of weeks after those extremely positive outcomes of coach Kevin McGuff’s third season in Columbus seemed inevitable, all of those achievements have been entirely wiped out.With the Buckeyes losing three of their last four games, including an embarrassing 82-63 loss to Michigan State in the semifinals of the Big Ten tournament, the one thing OSU needs before the NCAA tournament begins is what it had an abundance of when it last played in Columbus: an answer.OSU doesn’t have an answer as to what seed it will be when the NCAA tournament begins. It doesn’t have an answer as to how it came up empty-handed in the Big Ten regular-season title despite having a one-game lead with two games left to play. And it doesn’t have an answer as to what happened to one of the best offenses in the nation.The Buckeyes, who average 86.7 points per game, the third most in the country, had a season-low 20 points at the half against Michigan State in a game they trailed in by as many as 36 points.After the game, senior guard Cait Craft chalked much of that up to the ineffectiveness of fellow senior guard Ameryst Alston, who was held back by a sprained right wrist and didn’t score, but said there were still concerns about the way the team played as a whole.“Not having Ameryst hurt a little bit, but at the end of the day, we as a team didn’t come ready to play really until the last quarter,” Craft said. “Not having her does hurt, but it shouldn’t have been that detrimental to us. And I think we let that get in the way more than it should have, obviously.”McGuff said he doesn’t know what Alston’s status will be moving forward after the game, noting only the diagnosis of her injury and that he “hopes” she will be able to accelerate through her rehab and be good to go for the NCAA tournament.But missing Alston’s first-team All-Big Ten production was only a steep section of the mountain the Buckeyes were sliding down, not the point of departure from the top.The night before against Rutgers, in which Alston was perfectly healthy until the closing minutes, the Buckeyes only put up 26 points on the scoreboard at the half. They ended up winning the game 73-58 behind sophomore guard Kelsey Mitchell’s tournament-record 43 points, but, especially after losing their previous two games, the concerns were already in the air before the seismic semifinal debacle.A lot of the Buckeyes’ issues in the tournament were inexplicable, such as junior Shayla Cooper, a steady contributor off the bench throughout the year, suddenly being largely absent from the offense.Cooper averaged 13.5 points and 8.4 rebounds per game during the season, but against Rutgers she put up seven points on 2-of-10 shooting, and the next night she had just two points on 1-of-5 shooting through three quarters, including a second period absent from the floor.She ended up finishing off the night strong with 14 points in the garbage-time fourth quarter, hitting all six shot attempts. But Cooper has been one of the Buckeyes’ most valuable players all season long, and the need for her to step up inflated with Alston physically unable to shoot. Instead, she was nowhere to be found.After the Michigan State game, McGuff didn’t have an explanation or assessment for the sorry performance. He simply didn’t have an answer.“It didn’t have anything to do with effort or competitiveness,” McGuff said. “We have to learn from tonight that we’re going to hit some adversity again. I don’t know what it will be. Maybe it will be foul trouble, something. And how we react to it is going to determine everything.”Two weeks ago, OSU was a team that many were pegging as a Final Four contender. It had already beaten Maryland twice — the only two in-conference losses the Terrapins have had since joining the Big Ten — and had lost to powerhouses South Carolina and Notre Dame on the road by a combined 11 points.But now, the Buckeyes are trying to rebuild from the ground up with the NCAA tournament a week and a half away — trying to understand when it all turned around. “That’s the great thing about college basketball, you get a chance to tip it up again here before too long,” McGuff said. “And I think we have a great opportunity ahead of us. We just have to get back to the gym and kind of get back to being who we are.”The Buckeyes will learn their tournament seeding and opponent on Monday, and whether their first-round game will be set for March 18 or 19.